Surfing https://news.ycombinator.com/item?id=43724523
Oxygen mask https://news.ycombinator.com/item?id=43723317 https://news.ycombinator.com/item?id=43723706
As a pilot, it was eye opening to see first-hand what happens to me when experiencing hypoxia. The trainers were talking to me, and I was replying, but was unable to tell them what 17 minus 4.5 was.
The researchers, led by Corey O’Hern, developed computational models for all globular proteins in the Protein Data Bank, an online database, and measured their interior core regions to determine how densely packed they were. Every protein had a core packing fraction of 55%. That is, 55% of the space was occupied by atoms. That led the research team to two questions.
https://phys.org/news/2025-03-protein-mystery-core-fractions.html
funny, recommended treatment by ice chips
#scitisfaction
https://en.wikipedia.org/wiki/Sad_clown_paradox
just found an excuse for my silly jokes :)
#scitisfaction
As well as a total cell count, the study revealed something really interesting: if you group cells into categories based on their size, each size category contributes roughly the same amount to the mass of the body.
#scitisfaction
They discovered in recent years that tagging molecules with a sugar known as N-acetylgalactosamine (pGal) could mimic this process, sending the molecules to the liver where tolerance to them develops.
“The idea is that we can attach any molecule we want to pGal and it will teach the immune system to tolerate it,” explained Hubbell. “Rather than rev up immunity as with a vaccine, we can tamp it down in a very specific way with an inverse vaccine.”
#scitisfaction
www.theguardian.com/science/2…
After five years, 88% of patients who took the daily pill after the removal of their tumour were still alive, compared with 78% of patients treated with a placebo.
from HN:
This is a drug that targets lung cancer (~12% of cancers) and only one type of lung cancer (non-small cell lung cancer, ~80% of cases). It targets a particular mutated gene that occurs in about 30% of that subtype. And then, about 50% of those patients respond.
